Sensory Periphery: Coding Principals and Clinical Applications
The selection of which information is relevant for perceptual inference begins at the early stages of the sensory periphery. Many perceptual impairments such as low vision originate from a dysfunction of the peripheral stages in the sensory pathways. Therefore, identifying the coding principles at the periphery is of great importance for understanding perceptual inference as well as for clinical applications. Furthermore, it is less affected by feedback from other brain regions which makes it more suitable for developing accurate quantitative models of the neural response properties and computations. The central research questions are:
- How do different retinal ganglion cell types collectively encode the visual information?
- To what extent is retinal processing adapted to statistical regularities of natural images?
- How does neural processing in the retina interact with tuning mechanisms controlling the optics of the eye?
- Which features of retinal ganglion cell population responses are critical for visual perception?
- How can we use the obtained insights for clinical applications?
A1 Towards a complete representation of visual information at a single retinal location
A2 Processing of defocus in the retina
Schaeffel, Harmeling, Schoelkopf
A3 Optimization and comparison of electrical, chemical and optogenetic prosthetic stimulation in the retina
Muench, Panzeri, Zrenner